Genotoxicity

   In Vitro Genotoxicity Studies

• Bacterial Reverse Mutation Test (Ames test) using Salmonella typhimurium and E. coli WP2 uvrA – OECD TG 471 
• In Vitro Mammalian Chromosome Aberration Test using CHO – K1 cells / TK6 Cells / Human Peripheral Blood Lymphocytes (OECD TG 473)
• In Vitro Micronucleus test using CHO – K1 cells/ TK6 Cells / Human Peripheral Blood Lymphocytes (OECD TG 487)
• In Vitro Mammalian Cell Gene Mutation Test (HPRT assay) using V79 Cells (OECD TG 476)
• In Vitro Mammalian Cell Gene Mutation Test using Thymidine Kinase Gene (Mouse Lymphoma Assay, OECD TG 490)